The iSimangaliso Night Drive takes place on the eastern or western shores of the iSimangaliso Wetland Park. The night drive takes approximately three hours and begins at 20h00. Guests will be collected from and dropped off at their accommodation.

Drinks are served during the drive and in winter, blankets are provided. Guests may see animals such as hyenas, leopards, greater galagos, porcupines, African civets, genets and bush pigs. It is recommended that guests bring cameras, binoculars, warm clothes, and insect repellant with them on the drive.